Synthesis of a monophosphoryl lipid A derivative and its conjugation to a modified form of a tumor-associated carbohydrate antigen GM3.

نویسندگان

  • Qianli Wang
  • Jie Xue
  • Zhongwu Guo
چکیده

An efficient synthesis of a derivative of monophosphoryl lipid A suitable for coupling to various structures for the construction of glycoconjugate vaccines and its conjugation with an N-modified form of the tumor-associated antigen GM3 is presented.

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عنوان ژورنال:
  • Chemical communications

دوره 37  شماره 

صفحات  -

تاریخ انتشار 2009